U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07607340) titled 'Unloaded Minds - How Prolonged Unloading Shapes Human Performance in Lunar Gravity' on May 13.
Brief Summary: During spaceflight and lunar missions, reduced gravitational loading causes the muscles and nervous system to decondition rapidly. While muscle wasting is well documented, much less is known about how the brain and spinal cord adapt to the absence of normal mechanical loading - and how these central changes interact with muscle deterioration to impair movement control.
This study investigates how two weeks of simulated lower limb unloading affects the brain's movement programs (motor engrams), the functional connection betwe...