U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT07475949) titled 'Unknown Time of Onset Stroke RePerfusIon Without Advanced Imaging' on March 13.
Brief Summary: The benefit of intravenous tenecteplase for acute ischemic stroke with unknown time of onset, e.g. wake-up stroke, remains uncertain. This randomized study aims to assess the efficacy and safety of intravenous tenecteplase following non-contrast CT screening for acute ischemic stroke with unknown time of onset.
Study Start Date: April, 2026
Study Type: INTERVENTIONAL
Condition:
Acute Ischemic Stroke
Tenecteplase
Intervention:
DRUG: Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
Tenecteplase is administered as a single intraven...