Clinical Trial: Ultrasound-Guided Radiofrequency Ablation for Focal Adenomyosis

U.S., Oct. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07906535) titled 'Ultrasound-Guided Radiofrequency Ablation for Focal Adenomyosis' on Oct. 16.

Brief Summary: This single-center, single-arm, open-label study evaluates the efficacy and safety of ultrasound-guided radiofrequency ablation (RFA) in women with symptomatic focal adenomyosis who wish to preserve the uterus. RFA is performed transvaginally under general anesthesia using the Myoblate system. Participants are followed at 3, 6 and 12 months (optionally 24 months) with transvaginal ultrasound and validated questionnaires (VAS, PBAC, EQ-5D-5L). The primary outcomes are the changes in pain severity and menstrual blood loss at 6 and 12 months com...