U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT07476469) titled 'tVNS and Approach-Avoidance Behavior in Anhedonia and Anxiety' on Feb. 13.
Brief Summary: This study investigates if anhedonia and anxiety symptoms are associated with alterations in reinforcement learning, effort trade-offs for wins vs. punishments, and foraging behavior under threat. Moreover, it will investigate whether these processes can be influenced by a metabolic load and/or transcutaneous vagus nerve stimulation (tVNS). The project consists of (a) an online reinforcement learning study, used to characterize learning, reward sensitivity, and meta-cognition, and (b) a laboratory study in which participants first undergo fMRI...