Clinical Trial: Translational Health Research Into Vascular and Neurocognitive Effects of Weight Loss

U.S., May 19 -- ClinicalTrials.gov registry received information related to the study (NCT07592546) titled 'Translational Health Research Into Vascular and Neurocognitive Effects of Weight Loss' on May 03.

Brief Summary: The goal of this clinical trial is to learn about the nature of brain abnormalities associated with excess body fat in healthy adults aged 35-55. The main questions it aims to answer are:

* Will excessive fat be associated with brain abnormalities on MRI measures?

* Will weight loss change brain health on MRI measures?

Participants will:

* Self-administer study drug, semaglutide, once a week for 80 weeks

* Complete metabolic and basic body measurements

* Complete cognitive, mood, and dietary assessments

* Complete q...