U.S., April 22 -- ClinicalTrials.gov registry received information related to the study (NCT07542964) titled 'Transgender Analysis of Nephrological Studies Focused on Renal Metrics' on April 10.
Brief Summary: This study investigates how sex hormones affect kidney function in people undergoing gender-affirming hormone therapy (GAHT). We know men have a faster progression of kidney disease. Earlier studies suggest that the female sex hormone estradiol may have a protective effect on kidney function while the male sex hormone testosterone may have the opposite effect. But the reasons why this happens remain unclear. By studying participants undergoing (GAHT) we gain insight into the mechanisms by which testosterone and estradiol influence th...