U.S., July 31 -- ClinicalTrials.gov registry received information related to the study (NCT07738042) titled 'To Explore a Single-arm Phase II Study on Intestinal Microbiota Transplantation Combined With Neoadjuvant Immunotherapy and Chemoradiotherapy for Locally Advanced Rectal Cancer Under MSS/pMMR' on July 15.
Brief Summary: To evaluate the pathological complete response rate (pCR) of intestinal flora transplantation combined with short-course radiotherapy +CAPOX+ sintilimab in neoadjuvant therapy for locally advanced rectal cancer (pMMR/MSS type)
Study Start Date: July 31
Study Type: INTERVENTIONAL
Condition:
Locally Advanced Rectal Cancer (LARC)
Intervention:
DRUG: Sintilimab
Sintilimab 200mg Q3W 2 cycles
DRUG: CAPOX (oxaliplat...