U.S., Nov. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07921602) titled 'Tizanidine Premedication Versus Placebo for Laryngeal Mask Airway Insertion and Recovery in Adults Undergoing Ambulatory Surgery' on Oct. 27.

Brief Summary: This study will evaluate whether a single oral dose of tizanidine 4 mg given before surgery improves laryngeal mask airway (LMA) insertion conditions and postoperative recovery in adults undergoing elective ambulatory surgery under sevoflurane-based general anesthesia.

Eligible adults aged 18 to 65 years with American Society of Anesthesiologists (ASA) physical status I or II will be randomly assigned to receive either oral tizanidine 4 mg or a matching placebo 60 to 90 minutes ...