Clinical Trial: TIS for Improving Cognitive Impairment in Schizophrenia

U.S., June 16 -- ClinicalTrials.gov registry received information related to the study (NCT07647380) titled 'TIS for Improving Cognitive Impairment in Schizophrenia' on Feb. 27.

Brief Summary: This study aims to evaluate the efficacy, safety, and underlying neural mechanisms of TIS targeting the hippocampus in ameliorating cognitive impairment associated with schizophrenia (CIAS). Researchers will compare active TIS to a sham control to see if TIS works to treat CIAS. Participants will receive TIS twice a day for 2 weeks. Their clinical data, including the baseline clinical symptom scale score, cognitive function, E/I imbalance index recorded by EEG, and MRI data, will be collected at baseline, at the end of the 2-week intervention, and 4 ...