U.S., March 13 -- ClinicalTrials.gov registry received information related to the study (NCT07466173) titled 'The Importance of Insulin Action in the Brain for the Immune System During Physical Activity-Overweight' on March 06.
Brief Summary: The goal of this clinical trial is to clarify the interaction of central insulin action and physical activity with the immune system. Therefore, participants will undergo bicycle spiroergometer tests. This approach will be compared between days with insulin delivery to the brain as nasal spray and days with placebo spray. In another trial (NCT06552130) we already tested lean participants and found significant effects on circulating cytokines. In this amendment we will test overweight persons in which ...