U.S., Feb. 26 -- ClinicalTrials.gov registry received information related to the study (NCT07433426) titled 'The Impact of Shigellosis and Recommended Treatment in Children' on Feb. 20.
Brief Summary: The purpose of this study is to evaluate whether antibiotic treatment of non-dysentery Shigella associated watery diarrhea (NDSD) cases improves clinical outcomes and growth in children.
Children with NDSD seeking care for diarrhea at the study hospitals in Bangladesh and Zambia will be enrolled and randomized to receive Azithromycin or placebo (a look-alike substance that contains no drug). Enrolled children will be followed for three months with household visits.
The investigators will determine whether antibiotic treatment of NDSD reduce...