U.S., May 8 -- ClinicalTrials.gov registry received information related to the study (NCT07572903) titled 'The Efficacy and Safety of Temporal Interference Stimulation on Motor Symptoms of Parkinson's Disease' on April 27.
Brief Summary: This study aimed to observe the clinical efficacy and safety of single-target transcranial temporal stimulation (tTIS) intervention in Parkinson's disease (PD) patients and explore the neurophysiological mechanism of TIS intervention. The study was designed as a three-arm (A: GPi group, B: STN group, C: Sham group), randomized, double-blind, parallel-controlled trial. PD patients in the drug-off state (>=12 hours after drug withdrawal) were randomly assigned to receive either tTIS or sham stimulation targe...