U.S., March 24 -- ClinicalTrials.gov registry received information related to the study (NCT07488299) titled 'The Effect of PPI on Endoscopic Treatment of WON: a Multicenter Randomized Controlled Trial.' on March 17.
Brief Summary: In this multicenter, randomized controlled trial, patients with pancreatic walled-off necrosis based on inclusion and exclusion criteria will be randomly assigned in a 1:1 ratio to either receive intravenous infusion or oral administration of continuous proton pump inhibitor or to undergo no PPI (nPPI) therapy after endoscopic ultrasound-guided transluminal drainage/debridement. Clinical data and patient-reported outcomes will be systematically collected at baseline and during follow-up periods. The study aims t...