U.S., July 21 -- ClinicalTrials.gov registry received information related to the study (NCT07715552) titled 'The Effect of Nano Chitosan Surface Coating on White Spot Lesions Development in Clear Aligner Therapy Patients' on July 07.

Brief Summary: In this study, it was intended to investigate the effect of nano Chitosan (antimicrobial agent) coating on clear aligner orthodontic appliance if it reduces the incidence of white spot lesions (demineralization) of enamel surfaces.

Study Start Date: Oct. 12, 2025

Study Type: INTERVENTIONAL

Condition: White Spot Lesions

Intervention: OTHER: chitosan nanoparticles

Clear orthodontic aligners will be coated with nanoparticle sized Chitosan to investigate its anti-microbial effect on developme...