U.S., May 23 -- ClinicalTrials.gov registry received information related to the study (NCT07603934) titled 'The Effect of Different Intra-canal Medications on Postoperative Pain' on Nov. 18, 2025.
Brief Summary: The aim of this study is to assess the effect of ibuprofen, nitrofurantoin, and calcium hydroxide on postoperative pain after endodontic treatment of necrotic mandibular posterior teeth
Research question/hypothesis:
In patients with necrotic pulps in their mandibular posterior teeth, there would be no difference in the incidence and/or severity of postoperative pain after the use of ibuprofen, nitrofurantoin, or calcium hydroxide intracanal medications.
The study will evaluate postoperative pain after using either of the tested ...