Clinical Trial: Th Study Wants to Compare the Best Technique for Sinus Operation in CRSWNP

U.S., Jan. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07368361) titled 'Th Study Wants to Compare the Best Technique for Sinus Operation in CRSWNP' on Dec. 25, 2025.

Brief Summary: This randomized controlled trial aims to compare the efficacy and safety of reboot surgery versus conventional full house FESS in patients with refractory CRSwNP, focusing on:

1. Primary Outcome:

* Compare 24-month recurrence rates (defined as endoscopic polyp score >=2) 2. Secondary Outcomes:

* Recurrence-free survival (time to first recurrence), Quality of life improvement (SNOT-22 scores), Reduction in systemic corticosteroid use, Complication rates (synechiae, bleeding, infection) and Cost-effectiveness of each approac...