Clinical Trial: Testing a Non-Deceptive Placebo Intervention for Subclinical Depressive Symptoms

U.S., Oct. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07889908) titled 'Testing a Non-Deceptive Placebo Intervention for Subclinical Depressive Symptoms' on Oct. 06.

Brief Summary: Subclinical depression - depressive symptoms that fall below the threshold for major depressive disorder - is common in young adults and predicts later depressive episodes, yet it often goes untreated. This study tests whether a brief, remotely delivered non-deceptive (open-label) placebo intervention reduces subclinical depressive symptoms over approximately two weeks.

Participants aged 18-30 living in Ohio, with PHQ-8 scores in the 5-9 range, are randomly assigned to one of three groups: a non-deceptive placebo group, a bl...