U.S., Dec. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07304999) titled 'Surgical and Audiological Outcomes of Endoscopic Stapes Surgery' on Nov. 27.
Brief Summary: Otosclerosis is a pathological bone remodeling process that affects the middle and inner ears. It was first reported by Antonio Maria Valsalva in 1735 and subsequently described pathologically by Adam Politzer in 1839 .
In otosclerosis, the normal, dense endochondral bone of the otic capsule around the inner ear labyrinth is replaced by irregularly laid spongy bone, which subsequently hardens and leads to fixation of the stapes footplate . Otosclerosis causes progressive conductive hearing loss that typically presents with a normal tympanic ...