U.S., Aug. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07144891) titled 'sperDNA Fragmentation a a Predictor for Outcome After Varicocelectomy,m' on May 05.
Brief Summary: Varicocele is often associated with infertility and reduction in sperm quality, and it is one of the most common causes of reversible male infertility.
The exact mechanism of infertility caused due to varicocele formation remains unclear. One of the suggested theories is related to increased oxidative stress that causes sperm DNA damage, including DNA fragmentation, and is correlated with the decreased capacity of spermatozoa to fertilize oocytes during normal fertilization and assisted reproduction techniques. This is supported by th...