Clinical Trial: Serum Anti-enteric Neuronal Antibodies in Patients With Achalasia and Their Association With Clinical Profiles

U.S., March 6 -- ClinicalTrials.gov registry received information related to the study (NCT07451301) titled 'Serum Anti-enteric Neuronal Antibodies in Patients With Achalasia and Their Association With Clinical Profiles' on Feb. 26.

Brief Summary: Achalasia is a rare esophageal motility disorder characterized by impaired relaxation of the lower esophageal sphincter and progressive esophageal dilation. Increasing evidence suggests that autoimmune mechanisms may contribute to its development. Serum anti-enteric neuronal antibodies (AENA) have been reported more frequently in patients with achalasia than in healthy individuals.

This study aims to evaluate the association between AENA levels and disease severity in patients with achalasia. Sp...