Clinical Trial: Sepsis Multiomic Analysis & Risk sTratification in China

U.S., May 21 -- ClinicalTrials.gov registry received information related to the study (NCT07599644) titled 'Sepsis Multiomic Analysis & Risk sTratification in China' on May 14.

Brief Summary: Objectives:

1. Perform Bulk RNA-seq transcriptome sequencing on enrolled samples to screen sepsis-specific mRNA diagnostic biomarkers and evaluate their diagnostic efficacy for early sepsis in the ICU; establish a molecular risk stratification system for sepsis based on mRNA expression profiles, and clarify the immunobiological characteristics, clinical manifestation differences, and prognostic risk levels of each stratification.

2. Integrate core indicators screened from transcriptome sequencing, open-source databases, and previous studies to estab...