U.S., Nov. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07936747) titled 'Sensory Blockade and Swallow Variability' on Nov. 02.
Brief Summary: This prospective within-subject interventional study evaluated the effects of topical lidocaine-induced oropharyngeal sensory blockade on swallowing in healthy adults. Twenty participants underwent videofluoroscopic swallowing studies before and after sensory blockade. Five 10-mL thin-liquid swallows were assessed in each condition. The primary outcome was within-subject swallow-to-swallow variability in temporal swallowing measures. Secondary outcomes included mean swallowing timing, hyoid kinematics, upper esophageal sphincter opening, posterior pharyngeal wall d...