U.S., Aug. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07770035) titled 'School-aged Outcomes Post Hypoxic Ischaemic Encephalopathy' on July 09.
Brief Summary: Neonatal HIE increases the risk for cognitive impairments in childhood. Neonatal MRI brain scans are a strong predictor for outcome, however a normal scan has only a 35% sensitivity and 85% specificity for a normal outcome. This may be explained by variability in the brain's development over time in response to the initial insult.
This project will aim to develop a neonatal MRI machine learning algorithm that incorporates both initial injury and radiomic features associated with future brain development (based on school-age MRI) to predict school...