U.S., March 17 -- ClinicalTrials.gov registry received information related to the study (NCT07474558) titled 'SCALp Cooling for pReventing aLopecia With nEw anTibody-drug Conjugates' on Feb. 25.
Brief Summary: The goal of this interventional study is to determine if scalp cooling (by the Paxman Scalp Cooling System) reduces the extent and severity of alopecia in participants with advanced solid tumours receiving ADC.
The main question it aims to evaluate the efficacy of scalp cooling in reducing chemotherapy-induced alopecia in participants with advanced/metastatic solid tumours receiving antibody-drug conjugates (trastuzumab-deruxtecan, sacituzumab-govitecan, or datopotamab-deruxtecan), as assessed by blinded central dermatological revie...