U.S., Sept. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07839780) titled 'S-PRG Filler for Preventing White Spot Lesions During Orthodontic Treatment' on Sept. 17.

Brief Summary: White spot lesions are early areas of enamel demineralization that may develop during orthodontic treatment with fixed braces. This study aims to evaluate the effectiveness of S-PRG Barrier Coat in preventing white spot lesions during orthodontic treatment. The study will compare S-PRG Barrier Coat with 5% sodium fluoride varnish, a combination of S-PRG Barrier Coat and 5% sodium fluoride varnish, and a placebo. A total of 144 participants undergoing orthodontic treatment will be randomly assigned to one of four treatment groups...