U.S., Feb. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07418801) titled 'Role of RNA Metabolism Alterations in Persistent Immune Dysfunction After Sepsis' on Jan. 27.
Brief Summary: This study includes adult ICU patients with sepsis (according to SEPSIS 3.0) or critically ill non-septic patients with severe non-infectious conditions at Louis Mourier Hospital. It is a prospective multicentre observational study aiming to describe leukocyte transcriptome changes and molecular trajectories (endotypes) during the acute, recovery, and convalescence phases of sepsis. A total of 290 participants will be included: 200 septic patients, 50 critically ill non-septic patients, and 40 control participants.
Study Sta...