U.S., Sept. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07800598) titled 'Role of Allopurinol in Prevention of Complications Related to Decompensated Cirrhosis of Liver' on Aug. 13.
Brief Summary: Cirrhosis, a leading cause of global mortality, progresses to life-threatening complications like ascites, hepatic encephalopathy, and hepatorenal syndrome. Oxidative stress and gut-liver axis dysfunction drive disease progression. Allopurinol, a xanthine oxidase inhibitor, has shown potential in reducing complications in cirrhosis, but robust clinical evidence is lacking. This study will evaluate allopurinol's efficacy in preventing complications in decompensated cirrhosis.
This study aims to assess whether al...