U.S., Jan. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07317557) titled 'Remote Ischemic Conditioning for Cognitive Impairment in Cerebral Small Vessel Disease' on Dec. 08, 2025.
Brief Summary: This randomized, double-blind, sham-controlled trial aims to evaluate the effect of remote ischemic conditioning (RIC) on cognitive function in patients with cerebral small vessel disease-related mild cognitive impairment. Forty eligible participants will be randomized 1:1 to receive either RIC or sham RIC twice daily for 90 days in addition to standard medical therapy. The primary outcome is the change in Montreal Cognitive Assessment (MoCA) score from baseline to 90 days. Secondary outcomes include changes in whi...