U.S., Oct. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07880548) titled 'Remimazolam vs Propofol for Long-Term Sedation in Mechanically Ventilated ICU Patients' on Oct. 12.
Brief Summary: This multicenter, randomized, controlled, non-inferiority trial is designed to determine whether remimazolam is non-inferior to propofol for prolonged sedation in adult ICU patients requiring mechanical ventilation for >=48 hours. A total of 274 patients will be enrolled across 21 geographically diverse hospitals in China and allocated in a 1:1 ratio to receive either remimazolam or propofol using centralized, computer-generated block randomization. The primary endpoint is time to successful extubation-defined as extuba...