U.S., June 18 -- ClinicalTrials.gov registry received information related to the study (NCT07652632) titled 'Regenerative Endoscopy in Refractory Perianal Crohn's Disease' on June 05.
Brief Summary: Perianal fistulizing Crohn's disease (pCD) represents a severe phenotype of Crohn's disease, affecting approximately 20-30% of patients and resulting in chronic drainage, recurrent sepsis, impaired continence, and reduced quality of life. Despite optimization of biologics, antibiotics, and surgical drainage, durable healing remains difficult to achieve. Conventional surgical approaches such as curettage or seton management alone yield modest remission rates, and repeated procedures may compromise sphincter integrity.
Autologous mechanically pr...