U.S., Feb. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07435402) titled 'Reduction of Muscle Catabolism Through Brain Activation in Burn Patients' on Jan. 05.
Brief Summary: Patients with extensive burn injuries frequently develop severe skeletal muscle wasting and weakness as part of critical illness-related myopathy and neuropathy. This condition delays ventilator weaning, prolongs intensive care unit (ICU) and hospital stay, and contributes to long-term functional impairment and reduced quality of life. In burn patients, muscle loss is particularly pronounced during the early post-injury phase and is associated with mitochondrial dysfunction and altered neuromuscular signaling.
Effective strategies t...