Clinical Trial: Recurrence Mechanisms of Colorectal Adenoma After Resection and a Multi-Omics Research Protocol

U.S., July 7 -- ClinicalTrials.gov registry received information related to the study (NCT07683312) titled 'Recurrence Mechanisms of Colorectal Adenoma After Resection and a Multi-Omics Research Protocol' on June 28.

Brief Summary: We aim to establish a single-cell atlas of primary adenomas, recurrent adenomas, and paired normal mucosa, identify recurrence-associated cell subpopulations and transcriptional pathways, and construct a risk prediction model for recurrence (integrating multi-omics features and clinical variables). Ultimately, we propose a panel of biomarkers that can be used to optimize follow-up strategies and guide potential microbiome-based interventions.

Under the premise of meeting routine clinicopathological requirements...