U.S., June 19 -- ClinicalTrials.gov registry received information related to the study (NCT07658222) titled 'Prospective Investigation of Cirrhotic Cardiomyopathy in Humans' on June 15.
Brief Summary: Cirrhotic Cardiomyopathy (CCM) is a recognized complication of cirrhosis, but understudied despite recent retrospective data suggesting it may be common, affecting one in three patients with decompensated cirrhosis, and associated with significantly increased risk of death and adverse hepatic and cardiac events. Moreover, evidence from preclinical models and children suggest elevated bile acids in the blood may contribute to CCM, but data from adults with cirrhosis are scarce. Therefore, we are conducting the first contemporary prospective mu...