U.S., March 20 -- ClinicalTrials.gov registry received information related to the study (NCT07482969) titled 'Prevalence of Symptomatic Gastroesophageal Reflux Disease in Czech Children (Czech GERDKids)' on Nov. 23, 2025.
Brief Summary: This study aims to determine the prevalence of symptomatic gastroesophageal reflux disease (GERD) in children aged 8-9 years and 12-13 years in the Czech Republic. Participants are recruited through schools and complete a web-based questionnaire assessing reflux-related symptoms. Children reporting pyrosis or regurgitation undergo a stepwise diagnostic evaluation that includes a standardized proton pump inhibitor (PPI) trial, upper endoscopy when indicated, and 24-hour pH-impedance monitoring for those with...