Clinical Trial: Predictive Biomarkers for Precision Management of Pre-cancerous Cervical Neoplasia

U.S., Oct. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07895641) titled 'Predictive Biomarkers for Precision Management of Pre-cancerous Cervical Neoplasia' on Oct. 19.

Brief Summary: The goal of this observational study (retrospective cohort study) is to determine whether DNA methylation status in archived cervical cytology samples can predict regression, persistence, or progression of high-grade cervical dysplasia (HSIL/CIN2-3) in women who have previously undergone clinical management and follow-up.

The main questions it aims to answer are:

Can methylation status in archived cervical cytology samples predict histologic regression of HSIL (CIN2/3)? Does the addition of clinical factors, screening his...