Clinical Trial: Predicting Parkinson's Disease Before It Strikes: A Brain Imaging Study in At-Risk Individual

U.S., July 29 -- ClinicalTrials.gov registry received information related to the study (NCT07729748) titled 'Predicting Parkinson's Disease Before It Strikes: A Brain Imaging Study in At-Risk Individual' on July 15.

Brief Summary: This study aims to characterize neurodegeneration progression in patients with polysomnography (PSG)-confirmed longstanding idiopathic REM sleep behavior disorder (iRBD) and to develop a prognostic model for clinical evolution and earlier identification of cases at risk of short-term conversion to clinically defined Parkinson's disease (PD).

The study uses a multiparametric approach combining longitudinal clinical, neuropsychological, quantitative PSG, and multiparametric brain MRI markers (structural MRI, diffu...