U.S., Jan. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07330206) titled 'Precision Surgery for Pediatric Hydrocephalus: VPS vs. ETV With ML-Guided Prediction' on Dec. 29, 2025.
Brief Summary: Study type: Multicenter retrospective cohort study with prospective validation Primary purpose: To determine whether an individualized, imaging-guided treatment algorithm Ventriculoperitoneal shunt (VPS) vs endoscopic third ventriculostomy (ETV) improves 2-year neurodevelopmental outcomes in children =3 y, obstructive hydrocephalus, normal basal cisterns)?
* Does a machine-learning model (ETV-PS) using pre-operative MRI features accurately predict ETV success (AUC >=0.80) and thereby reduce unnecessary re-operation...