U.S., March 10 -- ClinicalTrials.gov registry received information related to the study (NCT07457814) titled 'Postoperative Pain and Analgesic Use After Total Knee Arthroplasty' on Feb. 24.
Brief Summary: This prospective observational study evaluates postoperative pain intensity and analgesic consumption in patients undergoing total knee arthroplasty (TKA) under different anesthesia techniques. Patients receive either general anesthesia with peripheral nerve block, spinal anesthesia with peripheral nerve block, spinal anesthesia alone, or general anesthesia with an epidural catheter. Pain scores (NRS), analgesic use, adverse effects, patient satisfaction, and the need for therapeutic interventions are assessed during the first 48 hours af...