U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT07475884) titled 'Postoperative Analgesia and Ventilation After Cardiac Surgery' on March 13.
Brief Summary: Cardiac surgery performed via median sternotomy is associated with significant postoperative pain due to extensive tissue trauma, sternal bone healing, and mediastinal retraction. Inadequately controlled postoperative pain represents an important source of morbidity in these patients and may adversely affect respiratory mechanics, leading to hypoventilation, atelectasis, and hypoxemia. These complications can delay extubation, prolong the duration of mechanical ventilation, and increase the length of stay in the intensive care unit (ICU). In ...