Clinical Trial: Polyp Pretreatment Device for SSL Diagnosis

U.S., May 23 -- ClinicalTrials.gov registry received information related to the study (NCT07601230) titled 'Polyp Pretreatment Device for SSL Diagnosis' on May 17.

Brief Summary: Colorectal cancer (CRC) is the third most common malignancy globally. Sessile serrated lesions (SSLs) account for 15-30% of CRC via the serrated pathway. Accurate SSL diagnosis relies on basal crypt features, which are often obscured by specimen curling during standard formalin fixation, leading to underdiagnosis. A novel polyp pretreatment device mechanically maintains mucosal flatness, ensuring vertical sectioning relative to the muscularis mucosae. This randomized, double-blind, parallel-controlled trial evaluates whether the device improves SSL diagnostic rate...