U.S., Feb. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07431645) titled 'Pilot Study of Radiation-Induced Xerostomia Treatment With Allogeneic Mesenchymal Stromal Stem Cells' on Feb. 18.
Brief Summary: This pilot interventional study evaluates the safety and preliminary efficacy of treatment with allogeneic mesenchymal stromal stem cells (MSCs) derived from umbilical cord tissue in patients with radiation-induced xerostomia after radiotherapy for head and neck cancer. Xerostomia is a frequent late adverse effect of radiotherapy and can significantly impair oral function and quality of life.
Participants receive a single administration of allogeneic MSCs as the study intervention and are followed for cli...