U.S., April 7 -- ClinicalTrials.gov registry received information related to the study (NCT07512427) titled 'Phase 1/2 Study of OPK-88006 in Healthy and Presumed MASH Participants' on Dec. 08, 2025.
Brief Summary: Two-part Phase 1/2 study of OPK-88006, including an open-label SAD phase in healthy participants and a double-blind, randomized, placebo-controlled MAD phase in participants with presumed MASH, to evaluate safety, PK, and MASH related pharmacodynamic changes compared to placebo.
Study Start Date: Dec., 2026
Study Type: INTERVENTIONAL
Condition:
MASH
Intervention:
DRUG: OPK-88006
Administered by subcutaneous injection
DRUG: Placebo
Administered by subcutaneous injection
Recruitment Status: NOT_YET_RECRUITING
Sponsor: OP...