U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07773246) titled 'Phase 1/2 Study of KRRO-121 in Healthy Volunteers and Patients With UCD' on Aug. 14.
Brief Summary: Phase 1/2 Study of KRRO-121 is a randomized, placebo-controlled study in Healthy Volunteers (Phase 1 SAD and MAD) and Study Participants with Urea Cycle Disorders (Phase 2). The primary objective of the study is to evaluate the safety of KRRO-121.
Study Start Date: Sept., 2026
Study Type: INTERVENTIONAL
Condition:
Urea Cycle Disorders, Inborn
Urea Cycle Disorders
Ornithine Transcarbamylase (OTC) Deficiency
Arginase 1 Deficiency
NAGS Deficiency
Carbamylphosphate Synthetase I
Ornithine Transporter Mitochondrial 1
Argininosuccinate S...