U.S., Aug. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07134491) titled 'Peripheral and Intrarenal B Cell Study in Antibody Mediated Transplant Rejection : Phenotypic and Transcriptional Study, Study of Reactivity' on July 08.
Brief Summary: Humoral rejection of kidney transplants is responsible for a large number of kidney graft losses in a context of increasing shortage.
Although it has been established that it is largely mediated by the alloreactive B lymphocyte, anti-B therapies are only partially effective.
The mechanisms behind the loss of tolerance are also poorly understood, and the triggers of rejection remain to be elucidated.
During this study, patients admitted for kidney graft biopsy for ...