U.S., April 23 -- ClinicalTrials.gov registry received information related to the study (NCT07545668) titled 'Periosteal Distraction With Skin Grafting for DFU' on April 14.
Brief Summary: This study is a single-center, prospective, randomized controlled trial aimed at evaluating whether periosteal distraction combined with autologous split-thickness skin grafting can significantly improve graft survival rate at postoperative day 14 compared with skin grafting alone in patients with diabetic foot ulcers (Wagner grade 2-3 or post-amputation). A total of 104 eligible patients will be randomly assigned to either the experimental group (periosteal distraction + skin grafting, n=52) or the control group (skin grafting alone, n=52). Secondary ou...