U.S., April 28 -- ClinicalTrials.gov registry received information related to the study (NCT07553286) titled 'Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial' on April 17.
Brief Summary: Periodontal disease in pregnant women has been implicated as a potential risk factor for adverse pregnancy outcomes, including being born preterm, small-for-gestational age, and/or low birth weight. Infants who have at least one of these outcomes, known as small vulnerable newborns (SVN)), are at increased risk of early death and poor infant growth and development. Rigorous, high-quality randomized trials are needed to evaluate whether improving the periodontal health of pregnant women can reduce the risk of advers...