Clinical Trial: PENTAGON: MS-Related Disability Worsening and Thalamic Volume Loss

U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07753928) titled 'PENTAGON: MS-Related Disability Worsening and Thalamic Volume Loss' on Aug. 03.

Brief Summary: PENTAGON is an observational, non-interventional, multicenter, prospective cohort study conducted at approximately 20 neurology centers and affiliated radiology centers across Germany. It investigates whether loss of thalamic volume (TVL) is an independent driver of disability progression in patients with relapsing-remitting multiple sclerosis (MS). The study observes two groups: patients with active MS (receiving or about to receive first- or second-line disease-modifying therapies) and patients with progressive MS. Over a 24-month primar...