U.S., July 22 -- ClinicalTrials.gov registry received information related to the study (NCT07715838) titled 'PEM, a Starting Point to Investigate ME/CFS' on March 29, 2024.
Brief Summary: Exercise is an important contributor to general health and is considered a potential remedy for chronic diseases. This is in strong contrast with the observation that in most myalgic encephalomyelitis (ME/CFS) patients exercise aggravates their symptoms. Recently, post-exertional malaise (PEM) is defined as the key symptom of ME/CFS. The etiology and pathophysiological mechanisms underlying ME/CFS are still unknown and objective diagnostic criteria are not available. Various hypotheses are postulated including disorders of several organ systems but the he...