U.S., May 14 -- ClinicalTrials.gov registry received information related to the study (NCT07585487) titled 'Paracetamol and Cefazolin Pharmacokinetics in Normal Weight and Overweight Children' on Jan. 13.
Brief Summary: Pharmacokinetic evaluations will be conducted to characterize the cefazolin plasma concentration-time profile, cefazolin penetration into subcutaneous adipose tissue, and paracetamol metabolization as assessed through blood sampling. The study population consists of children aged 2 to 15 years with either normal weight or overweight. All participants are admitted for a minor elective surgical procedure and will receive paracetamol and/or cefazolin as part of standard perioperative care.
During the procedure, multiple blood...