U.S., Jan. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07316660) titled 'Palmitoylethanolamide vs Ibuprofen for Pain After ESWL' on Dec. 19, 2025.
Brief Summary: Pain after extracorporeal shock wave lithotripsy (ESWL), a non-surgical procedure used to treat kidney stones, is common and is usually treated with non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen. However, NSAIDs may cause side effects in some patients, including stomach irritation and kidney problems.
Palmitoylethanolamide (PEA) is a naturally occurring substance in the body with anti-inflammatory and pain-relieving properties and has been shown to be safe in previous studies. This study aims to compare the effectiveness of PE...